Brief CV

Brief CV

Demetrios A. Spandidos

website: www.demetriosspandidos.com

Date and Place of Birth: 1947. Agios Constantinos, Sparta, Greece

Education:

  • B.Sc. in Chemistry, November 1971, Aristotelion University of Thesaloniki, Greece
  • Ph.D. in Biochemistry, January, 1976, McGill University, Montreal, Canada ,Title of Ph.D. Thesis: Genetics and Transcription of Reovirus
  • MRCPath, November 1988. Royal College of Pathologists, London, UK
  • D.Sc. in Genetics, July 1989. University of Glasgow, Scotland, UK, Title of D.Sc. Thesis: Studies on the role of ras gene in carcinogenesis
  • F.R.S.H. June 1994. The Royal Society of Health, London, UK
  • F.R.C.Path January 1997. The Royal College of Pathologists, London, UK
  • Specialised in Clinical Chemistry, 1998. Ministry of Health, Greece
  • FASA, 2005. The American Society of Angiology

Marital Status:Married to Dr Panayota D. Krempeniou (PhD in Law, Glasgow, UK) in 1976. Two children, born in 1977 (daughter Athanasia, BSc in Biochemistry, Glasgow, PhD in Molecular Biology, Cambridge, UK) and 1981 (son Nikiforos-Anastasios, BSc in Biochemistry, Glasgow, MSc in Molecular Biology, Edinburgh, PhD in Molecular and Cellular Biology, Glasgow, UK).

Citizenship:Greek

Professional Experience :

2015 – Present: Professor Emeritus, Medical School, University of Crete, Heraklion, Greece
1989 – 2014: Professor of Virology, Medical School, University of Crete, Heraklion, Greece
1990 – 2013: Director, Laboratory of Clinical Virology, University Hospital, Heraklion, Greece
2006 – 2010: Director, Laboratories of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, University Hospital, Heraklion, Greece
1988 – 1998: Director, Laboratory of Molecular Oncology and Biotechnology, Institute of Biological Research and Biotechnology, The National Hellenic Research Foundation, Athens, Greece
1981 – 1988: Member of the Senior Scientific Staff, Beatson Institute for Cancer Research, Glasgow, Scotland, UK
1985 – 1987: Head, Virology Programme, Hellenic Institute Pasteur, Athens, Greece
1985 – 1987:
(Feb-March each year)
Visiting Scientist and Guest lecturer “Genes and Cancer” course for medical, graduate and undergraduate students, Department of Pediatrics, Medical School, University of California, San Diego, USA
1979 – 1981: Centennial Fellow (MRC Canada), Beatson Institute for Cancer Research, Glasgow, Scotland, UK
1979: Director, Laboratory of Biochemistry, Medical Center of Athens Hospital, Athens, Greece
1978 – 1979: Epimelitis (Assistant Professor), Laboratory of Biochemical and Biological Research, Hellenic Anticancer Institute, Athens, Greece
1976 – 1978: Post-doctoral Fellow (MRC Canada), Department of Medical Genetics, University of Toronto, Toronto, Canada
July 1976: Cold Spring Harbor Laboratory, USA. Advanced Bacterial Genetics Course, including the recombinant DNA technology
1972 – 1976: Teaching Assistant, Department of Biochemistry, McGill University, Montreal, Canada
1970 – 1971: Research Assistant, Laboratory of Virology and Tissue Culture, Theagenion Cancer Institute, Thessaloniki, Greece

Additional Responsibilities:
Editor:
A. Journals

  • International Journal of Oncology (since 1992) (included in Science Citation Index and Index Medicus)
  • Oncology Reports (since 1994) (included in Science Citation Index and Index Medicus)
  • International Journal of Molecular Medicine (since 1998) (included in Science Citation Index and Index Medicus)
  • Molecular Medicine Reports (since 2008)
  • Experimental and Therapeutic Medicine (since 2010)
  • Oncology Letters (since 2010)
  • Biomedical Research* (since 2013)
  • Molecular and Clinical Oncology* (since 2013)
  • World Academy of Sciences Journal (since 2019)
  • Anticancer Research (Annual Special Issues from 1985 to 1990)
    *included in Science Citation Index and Index Medicus

B. Books in English

  • Current Perspectives on Molecular and Cellular Oncology, JAI Press Ltd, London, UK. Volume 1. Part A pp1-318, Part B pp1-332, 1992
  • Ras oncogenes, by D.A. Spandidos. Plenum Press. New York and London, pp1-323, 1989
  • The super-family of ras related genes, by D.A. Spandidos, Plenum Press, New York and London, pp1-337, 1992

C. Books in Greek
(Approved by the Ministry of Education for the Greek Universities)

      • Virology by D.A. Spandidos, Litsas Press, Athens pp1-260, 1991
      • Safety Manual for Universities and Research Centers by D.A. Spandidos, Litsas Press, Athens pp1-160, 1991
      • Molecular and Cellular Oncology by D.A. Spandidos, Litsas Press, Athens, pp1-448, 1992
      • Clinical Virology by D.A. Spandidos, Lychnia Press, Athens, pp1-364, 1998
      • Molecular Oncology by D.A. Spandidos, Lychnia Press, Athens, pp1-521, 2000

(The above books have been approved by the Ministry of Education for the Greek Universities)

  • Churches and Monasteries in the Municipality of Pellana in Lakedemon, pp1-140, Spandidos Publications, Athens, 2001
  • The contribution of Fighters of Greek Revolution in 1821 from the Municipality of Pellana by D.A. Spandidos pp1-638, Spandidos Publications, Athens 2009
  • Medicine in Ancient Sparta by I.N. Tsoulogiannis and D.A. Spandidos, pp1-170, Spandidos Publications, Athens, 2007
  • The contribution of Fighters of Greek Revolution in 1821 from the Municipality of Pellana by D.A. Spandidos pp1-638, Spandidos Publications, Athens 2009
  • Lakedaimon and the Greek Revolution 1821, pp1-584, Spandidos Publications, Athens 2014.

D. Books in Greek/English

  • Asclepius Sanctuaries in Laconia, pp1-75, Spandidos Publications, Athens, 2005

Member of the Editorial Boards:

  • Anticancer Research (1985-1993)
  • In vivo (1988-1993)
  • European Journal of Cancer-Oral Oncology (since 1992-2007)
  • Molecular and Cellular Differentiation (1993-1995)
  • Cancer Molecular Biology (1994-2000)
  • Pathology Oncology Research (since 1995)
  • The International Journal of Biological Markers (since 1995)
  • Minerva Biotechnologica (since 1996)
  • Journal of Balkan Union of Oncology (since 1996)
  • Journal of Cellular and Molecular Medicine (2001-2006)
  • Austral-Asian Journal of Cancer (since 2003)
  • Current Cancer Therapy Reviews (2004-2014)
  • Acta Pharmacologica Sinica (since 2005)
  • The Open Neuroscience Journal (2007-2014)
  • Romanian Archives of Microbiology and Immunology (since 2007)
  • The Open Cancer Journal (since 2007)
  • The Open Neurology Journal (since 2007)
  • The Open Dermatology Journal (since 2007)
  • Journal of Taibah University Medical Sciences (since 2007)
  • Journal of Ovarian Research (since 2007)
  • Immunopathological Diseases and Therapeutics (since 2009)
  • Journal of Chinese Integrative Medicine (since 2010)
  • Critical Reviews in Oncogenesis (since 2011)

Meetings Organizer:

1. Chairman, Organizing Committee of the 35th Meeting of the European Tissue Culture Society (ETCS), Athens, Greece, 1987

2. Chairman, Organizing Committee and the 25th Meeting of the Cell, Tissue and Organ Culture Study Group (CTOC) Athens, Greece, 1987

3. Director, NATO Advanced Research Workshop on “Ras oncogenes”, Athens, Greece, 1988

4. Chairman, Organizing Committee of the European Association for Cancer Research Sponsored Spring Symposium on “Oncogenes and Onco-supressor Genes”, Athens, Greece, 1989

5. Director, FEBS Advanced Lecture Course on “The Role of Oncogenes and Biological Response Modifiers in Tumor Invasion and Metastasis”. Athens, Greece, 1989

6. Chairman, Organizing Committee of the International Conference on “Cell Differentiation/Oncogenesis”. Athens, Greece, 1990

7. Director, NATO Advanced Research Workshop on “The Super-family of ras Related Genes”, Agia Pelagia, Crete, Greece, 1991

8. Chairman, Organizing Committee of the International Seminar Course entitled “Breast Cancer: Therapeutic Strategy and Molecular Biology”. Agia Pelagia, Crete, Greece, 1991

9. Chairman, Organizing Committee of the International Seminar Course entitled “Colorectal Cancer: Therapeutic Strategy and Molecular Biology”. Vouliagmeni, Athens, Greece, 1992

10. Chairman, Organizing Committe of the “1st World Congress on Advances in Oncology”, Athens, Greece, 1995

11. Chairman, Organizing Committee of the “Oncology 1996” Conference, Island of Kos, Greece, 1996

12. Chairman, Organizing Committee of the “2nd World Congress on Advances in Oncology”, Athens, Greece, 1997

13. Chairman, Organizing Committee of the “3rd World Congress on Advances in Oncology”, Hersonissos, Crete, Greece, 1998

14. Chairman, Organizing Committee of the “1st International Symposium on Molecular Medicine”, Hersonissos, Crete, Greece, 1998

15. Chairman, Organizing Committee of the “Seminar on Cancer Research”, of the Balkan School of Oncology, Athens, Greece, 1998

16. Chairman, Organizing Committee of the “4th World Congress on Advances in Oncology”, Vouliagmeni, Athens, Greece, 1999

17. Chairman, Organizing Committee of the “2nd International Symposium on Molecular Medicine”,Vouliagmeni, Athens, Greece, 1999

18. Chairman, Organizing Committee of the “5th World Congress on Advances in Oncology”, Hersonissos, Crete, Greece, 2000

19. Chairman, Organizing Committee of the “3rd International Symposium on Molecular Medicine”, Hersonissos, Crete, Greece, 2000

20. Chairman, Organizing Committee of the “6th World Congress on Advances in Oncology”, Hersonissos, Crete, Greece, 2001

21. Chairman, Organizing Committee of the “4th International Symposium on Molecular Medicine”, Hersonissos, Crete, Greece, 2001

22. Chairman, Organizing Committee of the “7th World Congress on Advances in Oncology”, Hersonissos, Crete, Greece, 2002

23. Chairman, Organizing Committee of the “5th International Symposium on Molecular Medicine”, Hersonissos, Crete, Greece, 2002

24. Chairman, Organizing Committee of the “8th World Congress on Advances in Oncology”, Hersonissos, Crete, Greece, 2003

25. Chairman, Organizing Committee of the “6th International Symposium on Molecular Medicine”, Hersonissos, Crete, Greece, 2003

26. Chairman, Organizing Committee of the “9th World Congress on Advances in Oncology”, Hersonissos, Crete, Greece, 2004

27. Chairman, Organizing Committee of the “7th International Symposium on Molecular Medicine”, Hersonissos, Crete, Greece, 2004

28. Chairman, Organizing Committee of the “10th World Congress on Advances in Oncology”, Hersonissos, Crete, Greece, 2005

29. Chairman, Organizing Committee of the “8th International Symposium on Molecular Medicine”, Hersonissos, Crete, Greece, 2005

30. Chairman, Organizing Committee of the “11th World Congress on Advances in Oncology”, Hersonissos, Crete, Greece, 2006

31. Chairman, Organizing Committee of the “9th International Symposium on Molecular Medicine”,Hersonissos, Crete, Greece, 2006

32. Chairman, Organizing Committee of the “12th World Congress on Advances in Oncology”, Hersonissos, Crete, Greece, 2007

33. Chairman, Organizing Committee of the “10th International Symposium on Molecular Medicine”, Hersonissos, Crete, Greece, 2007

34. Chairman, Organizing Committee of the â”13th World Congress on Advances in Oncologyâ”, Hersonissos, Crete, Greece, 2008

35. Chairman, Organizing Committee of the â”11th International Symposium on Molecular Medicineâ”, Hersonissos, Crete, Greece, 2008

36. Chairman, Organizing Committee of the â”14th World Congress on Advances in Oncologyâ”, Loutraki, Greece, 2009

37. Chairman, Organizing Committee of the â”12th International Symposium on Molecular Medicineâ”, Loutraki, Greece, 2009

38. Chairman, Organizing Committee of the â”15th World Congress on Advances in Oncologyâ”, Loutraki, Greece, 2010

39. Chairman, Organizing Committee of the â”13th International Symposium on Molecular Medicineâ”, Loutraki, Greece, 2010

40. Chairman, Organizing Committee of the â”16th World Congress on Advances in Oncologyâ”, Rhodes, Greece, 2011

41. Chairman, Organizing Committee of the â”17th World Congress on Advances in Oncologyâ”, Hersonissos, Crete, Greece, 2012

42. Chairman, Organizing Committee of the â”14th International Symposium on Molecular Medicineâ”, Rhodes, Greece, 2011

43. Chairman, Organizing Committee of the â”15th International Symposium on Molecular Medicineâ”, Hersonissos, Crete, Greece, 2012

44. Chairman, Organizing Committee of the ‘18th World Congress on Advances in Oncology’, Hersonissos, Crete, Greece, 2013

45. Chairman, Organizing Committee of the ‘16th International Symposium on Molecular Medicine’, Hersonissos, Crete, Greece, 2013

46. Chairman, Organizing Committee of the ‘19th World Congress on Advances in Oncology’, Athens, Greece, 2014

47. Chairman, Organizing Committee of the ‘17th International Symposium on Molecular Medicine’, Athens, Greece, 2014

48. Chairman, Organizing Committee of the ‘20th International Symposium on Molecular Medicine’, Athens, Greece, 2015

49. Chairman, Organizing Committee of the ‘18th International Symposium on Molecular Medicine’, Athens, Greece, 2015

50. Chairman, Organizing Committee of the ‘21st International Symposium on Molecular Medicine’, Athens, Greece, 2016

51. Chairman, Organizing Committee of the ‘19th International Symposium on Molecular Medicine’, Athens, Greece, 2016

52. Chairman, Organizing Committee of the ‘22nd International Symposium on Molecular Medicine’, Athens, Greece, 2017

53. Chairman, Organizing Committee of the ‘20th International Symposium on Molecular Medicine’, Athens, Greece, 2017

54. Chairman, Organizing Committee of the ‘21st International Symposium on Molecular Medicine’, Bangkok, Thailand, 2018

55. Chairman, Organizing Committee of the ‘23rd World Congress on Advances in Oncology’, Athens, Greece, 2018

56. Chairman, Organizing Committee of the ‘22nd International Symposium on Molecular Medicine’, Athens, Greece, 2018

57. Chairman, Organizing Committee of the ‘23rd International Symposium on Molecular Medicine’, Bangkok, Thailand, 2019

58. Chairman, Organizing Committee of the ‘24th World Congress on Advances in Oncology’, Sparta, Greece, 2019

59. Chairman, Organizing Committee of the ‘24th International Symposium on Molecular Medicine’, Sparta, Greece, 2019

Advisory and Administrative Responsibilities:

  • Member of the Advisory Board, Institute of Developmental Neuroscience and Aging (1986-1990)
  • Member of the Board of Governors and Nomination Committee of the International Association for Breast Cancer Research (1991-1998)
  • Member of the Scientific Board of the Roy Castle International Center for Lung Cancer Research, Liverpool, UK (since 1996-2004)
  • Member of the Board of Governors of Euroscience (1997-2000)
  • Director of the section of Laboratory Medicine, Medical School, University of Crete, Heraklion, Greece
  • Member of the Board of Directors, Medical School, University of Crete, Heraklion, Greece
  • Member of the Committee of Graduate Studies, Medical School, University of Crete, Heraklion, Greece

Honors/Awards:

  • Honorary Member of the Hellenic Society of Mastology, Athens, Greece (1987)
  • Corresponding Member of the Academia National de Medicina de Buenos Aires, Buenos Aires, Argentina (1989)
  • Honorary Member of the Hellenic Society for Lung Cancer, Pireas, Greece (1990)
  • Doctor Honoris Causa of “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania (2002)
  • Honorary Member of the Hellenic Society for Toxicology, Greece (2002)
  • Doctor Honoris Causa of “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania (2004)
  • Visiting Professor, University of Catania, Italy (2005)
  • Honorary Member of the Balkan Union of Oncology (2007)
  • Honorary Member of the Hellenic Society of Surgical Oncology (2011)
  • Honorary Professor, Fujian University, P.R. China (2013)
  • Visiting Professor, Kyoto University, Japan (2014)

Publications (By July 2020)
Professor D.A. Spandidos has authored more than 900 publications in English in 200 different international journals and more than 50 publications in Greek journals. His work has received over 26.500 citations. His major findings have been discussed in the journals Nature, Science, New Scientist and The Economist among others.

Communications (By July 2020)
Professor D.A. Spandidos has participated with more than 1000 communications and invited talks in International Conferences.

Ph.D. Supervisor:
More than 100 graduate students have obtained their PhD degree in Greece under the supervision of Professor D.A. Spandidos and most of them are pursuing careers abroad in leading institutions in the field of cancer research as shown by work published in top biomedical journals.

Research Achievements:
Among his most significant work is included the discovery of avian reovirus (DA Spandidos and AF Graham, J Virol 19: 977, 1976 – more than 100 citations), the discovery of cellular oncogenes by gene transfer (DA Spandidos and L Siminovitch, Cell 12: 675, 1977 and DA Spandidos and L Siminovitch, Nature 271: 259, 1978), the transfer of human globin genes to hemopoietic cells (DA Spandidos and J Paul, EMBO J 1: 15, 1982 – more than 65 citations), the involvement of ras genes in colon tumours (DA Spandidos and IB Kerr, Br J Cancer 49: 681, 1984 – more than 210 citations), the mechanism of transformation by ras genes (DA Spandidos and NM Wilkie, Nature 310: 469, 1984 – more than 520 citations), the role of ras and myc genes in apoptosis (AH Wyllie, KA Rose, RG Morris, CM Steel, E Foster and DA Spandidos, Br J Cancer 56: 251, 1987 – more than 200 citations), the involvement of p53 in head and neck carcinomas (JK Field, DA Spandidos, A Malliri, JR Gosney, M Yiagnisis and PM Stell, Br J Cancer 64: 573, 1991 – more than 250 citations) among others, the involvement of BRAF and RKIP genes in squamous cell carcinoma (Zaravinos A, Kanellou P, Baritaki S, Bonavida B and Spandidos DA, Cell Cycle 8: 1, 2009) and the genetic analysis of urinary bladder cancer (Zaravinos A, Lambrou GI, Boulalas I, Delakas D and Spandidos DA, PLoS ONE 6: e18135, 2011 and Zaravinos A, Lambrou GI, Volanis D, Delakas D and Spandidos DA, PLoS ONE 6: e18255, 2011) and the foundation of Paediatric Virology (Mammas IN and Spandidos DA, Exp Ther Med 12: 539-540, 2016 and Mammas IN and Spandidos DA, Exp Ther Med 12: 541-549, 2016).